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The Effects of Controlled Release of Neurotrophin-3 from PCLA Scaffolds on the Survival and Neuronal Differentiation of Transplanted Neural Stem Cells in a Rat Spinal Cord Injury Model

Neural stem cells (NSCs) have emerged as a potential source for cell replacement therapy following spinal cord injury (SCI). However, poor survival and low neuronal differentiation remain major obstacles to the use of NSCs. Biomaterials with neurotrophic factors are promising strategies for promotin...

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Detalles Bibliográficos
Autores principales: Tang, Shuo, Liao, Xiang, Shi, Bo, Qu, Yanzhen, Huang, Zeyu, Lin, Qiang, Guo, Xiaodong, Pei, Fuxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162607/
https://www.ncbi.nlm.nih.gov/pubmed/25215612
http://dx.doi.org/10.1371/journal.pone.0107517