Cargando…
The Effects of Controlled Release of Neurotrophin-3 from PCLA Scaffolds on the Survival and Neuronal Differentiation of Transplanted Neural Stem Cells in a Rat Spinal Cord Injury Model
Neural stem cells (NSCs) have emerged as a potential source for cell replacement therapy following spinal cord injury (SCI). However, poor survival and low neuronal differentiation remain major obstacles to the use of NSCs. Biomaterials with neurotrophic factors are promising strategies for promotin...
Autores principales: | Tang, Shuo, Liao, Xiang, Shi, Bo, Qu, Yanzhen, Huang, Zeyu, Lin, Qiang, Guo, Xiaodong, Pei, Fuxing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162607/ https://www.ncbi.nlm.nih.gov/pubmed/25215612 http://dx.doi.org/10.1371/journal.pone.0107517 |
Ejemplares similares
-
PclR is a transcriptional activator of the gene that encodes the pneumococcal collagen-like protein PclA
por: Moreno-Blanco, Ana, et al.
Publicado: (2022) -
3D printed PCLA scaffold with nano‐hydroxyapatite coating doped green tea EGCG promotes bone growth and inhibits multidrug‐resistant bacteria colonization
por: Zhang, Xiangchun, et al.
Publicado: (2022) -
The Modulation of Neurotrophin and Epigenetic Regulators: Implication for Astrocyte Proliferation and Neuronal Cell Apoptosis After Spinal Cord Injury
por: Kim, Jong Heon, et al.
Publicado: (2016) -
Targeting Neurotrophins to Specific Populations of Neurons: NGF, BDNF, and NT-3 and Their Relevance for Treatment of Spinal Cord Injury
por: Keefe, Kathleen M., et al.
Publicado: (2017) -
Neurotrophin‐3 released from implant of tissue‐engineered fibroin scaffolds inhibits inflammation, enhances nerve fiber regeneration, and improves motor function in canine spinal cord injury
por: Li, Ge, et al.
Publicado: (2018)