Sheep Lung Segmental Delivery Strategy Demonstrates Adenovirus Priming of Local Lung Responses to Bacterial LPS and the Role of Elafin as a Response Modulator

Viral lung infections increase susceptibility to subsequent bacterial infection. We questioned whether local lung administration of recombinant adenoviral vectors in the sheep would alter the susceptibility of the lung to subsequent challenge with bacterial lipopolysaccharide (LPS). We further quest...

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Detalles Bibliográficos
Autores principales: Brown, Thomas I., Collie, David S., Shaw, Darren J., Rzechorzek, Nina M., Sallenave, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162618/
https://www.ncbi.nlm.nih.gov/pubmed/25216250
http://dx.doi.org/10.1371/journal.pone.0107590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162618/
https://www.ncbi.nlm.nih.gov/pubmed/25216250
http://dx.doi.org/10.1371/journal.pone.0107590

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