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Sheep Lung Segmental Delivery Strategy Demonstrates Adenovirus Priming of Local Lung Responses to Bacterial LPS and the Role of Elafin as a Response Modulator
Viral lung infections increase susceptibility to subsequent bacterial infection. We questioned whether local lung administration of recombinant adenoviral vectors in the sheep would alter the susceptibility of the lung to subsequent challenge with bacterial lipopolysaccharide (LPS). We further quest...
Autores principales: | Brown, Thomas I., Collie, David S., Shaw, Darren J., Rzechorzek, Nina M., Sallenave, Jean-Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162618/ https://www.ncbi.nlm.nih.gov/pubmed/25216250 http://dx.doi.org/10.1371/journal.pone.0107590 |
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