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Fructose-1, 6-bisphosphatase opposes renal carcinoma progression

Clear cell renal cell carcinoma (ccRCC), the most frequent form of kidney cancer(1), is characterized by elevated glycogen and fat deposition(2). These consistent metabolic alterations are associated with normoxic stabilization of hypoxia inducible factors (HIFs)(3), secondary to von hippel-lindau (...

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Detalles Bibliográficos
Autores principales: Li, Bo, Qiu, Bo, Lee, David S.M., Walton, Zandra E., Ochocki, Joshua D., Mathew, Lijoy K., Mancuso, Anthony, Gade, Terence P.F., Keith, Brian, Nissim, Itzhak, Simon, M. Celeste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162811/
https://www.ncbi.nlm.nih.gov/pubmed/25043030
http://dx.doi.org/10.1038/nature13557