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Over-expression, purification and isotopic labeling of a tag-less human glucose-dependent insulinotropic polypeptide (hGIP)

Glucose-dependent insulinotropic polypeptide (GIP), a gut peptide released in response to food intake brings about secretion of insulin in a glucose-dependent manner upon binding to its receptor, GIPR. GIP–GIPR has emerged as a new vista for anti-diabetic drug discovery and their interaction is bein...

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Detalles Bibliográficos
Autores principales: Chandarana, Rakesh C., Vikrant, Varma, Ashok K., Saran, Anil, Coutinho, Evans C., D’Souza, Jacinta S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162901/
https://www.ncbi.nlm.nih.gov/pubmed/28324382
http://dx.doi.org/10.1007/s13205-013-0181-x