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Global distribution of malaria-resistant MHC-HLA alleles: the number and frequencies of alleles and malaria risk
BACKGROUND: The major histocompatibility complex (MHC) is the most polymorphic genetic region in vertebrates, but the origin of such genetic diversity remains unresolved. Several studies have demonstrated at the within-population level that individuals harbouring particular alleles can be less or mo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162943/ https://www.ncbi.nlm.nih.gov/pubmed/25187124 http://dx.doi.org/10.1186/1475-2875-13-349 |