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Tanshinone IIA pretreatment protects free flaps against hypoxic injury by upregulating stem cell-related biomarkers in epithelial skin cells

BACKGROUND: Partial or total flap necrosis after flap transplantation is sometimes encountered in reconstructive surgery, often as a result of a period of hypoxia that exceeds the tolerance of the flap tissue. The purpose of this study was to determine whether Tanshinone IIA (TSA) pretreatment can p...

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Detalles Bibliográficos
Autores principales: Xu, Zihan, Wu, Lijun, Sun, Yaowen, Guo, Yadong, Qin, Gaoping, Mu, Shengzhi, Fan, Ronghui, Wang, Benfeng, Gao, Wenjie, Zhang, Zhenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162953/
https://www.ncbi.nlm.nih.gov/pubmed/25186638
http://dx.doi.org/10.1186/1472-6882-14-331