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In Pichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response

Protein production in yeasts is related to the specific growth rate μ. To elucidate on this correlation, we studied the transcriptome of Pichia pastoris at different specific growth rates by cultivating a strain secreting human serum albumin at μ = 0.015 to 0.15 h(–1) in glucose-limited chemostats....

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Detalles Bibliográficos
Autores principales: Rebnegger, Corinna, Graf, Alexandra B, Valli, Minoska, Steiger, Matthias G, Gasser, Brigitte, Maurer, Michael, Mattanovich, Diethard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162992/
https://www.ncbi.nlm.nih.gov/pubmed/24323948
http://dx.doi.org/10.1002/biot.201300334