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Early evaluation of the therapeutic effect of denosumab on tartrate-resistant acid phosphatase 5b expression in a giant cell tumor of bone: a case report

BACKGROUND: Giant cell tumor of bone is an osteolytic, usually benign, tumor characterized by the infiltration of osteoclast-like giant cells. The receptor activator of nuclear factor kappa-B ligand pathway has been shown to play a key role in the pathogenesis of giant cell tumor. Treatment for refr...

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Detalles Bibliográficos
Autores principales: Watanabe, Naoto, Matsumoto, Seiichi, Shimoji, Takashi, Ae, Keisuke, Tanizawa, Taisuke, Gokita, Tabu, Motoi, Noriko, Ueno, Teruko, Koizumi, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163159/
https://www.ncbi.nlm.nih.gov/pubmed/25193435
http://dx.doi.org/10.1186/1756-0500-7-608