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Glycoprotein IIb/IIIa and P2Y(12) Induction by Oligochitosan Accelerates Platelet Aggregation

Platelet membrane receptor glycoprotein IIb/IIIa (gpiibiiia) is a receptor detected on platelets. Adenosine diphosphate (ADP) activates gpiibiiia and P2Y(12), causing platelet aggregation and thrombus stabilization during blood loss. Chitosan biomaterials were found to promote surface induced hemost...

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Detalles Bibliográficos
Autores principales: Periayah, Mercy Halleluyah, Halim, Ahmad Sukari, Yaacob, Nik Soriani, Mat Saad, Arman Zaharil, Hussein, Abdul Rahim, Abdul Rashid, Ahmad Hazri, Ujang, Zanariah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163351/
https://www.ncbi.nlm.nih.gov/pubmed/25247182
http://dx.doi.org/10.1155/2014/653149