The Mcm2-7 Replicative Helicase: A Promising Chemotherapeutic Target

Numerous eukaryotic replication factors have served as chemotherapeutic targets. One replication factor that has largely escaped drug development is the Mcm2-7 replicative helicase. This heterohexameric complex forms the licensing system that assembles the replication machinery at origins during ini...

Descripción completa

Detalles Bibliográficos
Autores principales: Simon, Nicholas E., Schwacha, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163376/
https://www.ncbi.nlm.nih.gov/pubmed/25243149
http://dx.doi.org/10.1155/2014/549719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163376/
https://www.ncbi.nlm.nih.gov/pubmed/25243149
http://dx.doi.org/10.1155/2014/549719

Ejemplares similares