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The Mcm2-7 Replicative Helicase: A Promising Chemotherapeutic Target

Numerous eukaryotic replication factors have served as chemotherapeutic targets. One replication factor that has largely escaped drug development is the Mcm2-7 replicative helicase. This heterohexameric complex forms the licensing system that assembles the replication machinery at origins during ini...

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Detalles Bibliográficos
Autores principales:	Simon, Nicholas E., Schwacha, Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163376/ https://www.ncbi.nlm.nih.gov/pubmed/25243149 http://dx.doi.org/10.1155/2014/549719

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