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Lentivirus Mediated siRNA against GluN2B Subunit of NMDA Receptor Reduces Nociception in a Rat Model of Neuropathic Pain

Although neuropathic pain (NP) is still not fully understood by scientists and clinicians alike, studies suggest that N-methyl-D-aspartate (NMDA) receptors play an important role in the induction and maintenance of NP. A promising treatment for NP is through the downregulation of NMDA subunit GluN2B...

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Detalles Bibliográficos
Autores principales: Wu, Feixiang, Pan, Ruirui, Chen, Jiaying, Sugita, Megumi, Chen, Caiyang, Tao, Yong, Yu, Weifeng, Sun, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163390/
https://www.ncbi.nlm.nih.gov/pubmed/25243192
http://dx.doi.org/10.1155/2014/871637