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Identification and Analysis of Driver Missense Mutations Using Rotation Forest with Feature Selection

Identifying cancer-associated mutations (driver mutations) is critical for understanding the cellular function of cancer genome that leads to activation of oncogenes or inactivation of tumor suppressor genes. Many approaches are proposed which use supervised machine learning techniques for predictio...

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Detalles Bibliográficos
Autores principales: Du, Xiuquan, Cheng, Jiaxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163459/
https://www.ncbi.nlm.nih.gov/pubmed/25250338
http://dx.doi.org/10.1155/2014/905951