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Delivery of Human EV71 Receptors by Adeno-Associated Virus Increases EV71 Infection-Induced Local Inflammation in Adult Mice

Enterovirus71 (EV71) is now recognized as an emerging neurotropic virus in Asia and one major causative agent of hand-foot-mouth diseases (HFMD). However potential animal models for vaccine development are limited to young mice. In this study, we used an adeno-associated virus (AAV) vector to introd...

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Detalles Bibliográficos
Autores principales: Hsiao, Hung-Bo, Chou, Ai-Hsiang, Lin, Su-I, Lien, Shu-Pei, Liu, Chia-Chyi, Chong, Pele, Chen, Chih-Yeh, Tao, Mi-Hua, Liu, Shih-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163470/
https://www.ncbi.nlm.nih.gov/pubmed/25243194
http://dx.doi.org/10.1155/2014/878139