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Dynamic Alu Methylation during Normal Development, Aging, and Tumorigenesis
DNA methylation primarily occurs on CpG dinucleotides and plays an important role in transcriptional regulations during tissue development and cell differentiation. Over 25% of CpG dinucleotides in the human genome reside within Alu elements, the most abundant human repeats. The methylation of Alu e...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163490/ https://www.ncbi.nlm.nih.gov/pubmed/25243180 http://dx.doi.org/10.1155/2014/784706 |