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Dynamic Alu Methylation during Normal Development, Aging, and Tumorigenesis

DNA methylation primarily occurs on CpG dinucleotides and plays an important role in transcriptional regulations during tissue development and cell differentiation. Over 25% of CpG dinucleotides in the human genome reside within Alu elements, the most abundant human repeats. The methylation of Alu e...

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Detalles Bibliográficos
Autores principales: Luo, Yanting, Lu, Xuemei, Xie, Hehuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163490/
https://www.ncbi.nlm.nih.gov/pubmed/25243180
http://dx.doi.org/10.1155/2014/784706

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