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The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice

Shroom3 is an actin-associated regulator of cell morphology that is required for neural tube closure, formation of the lens placode, and gut morphogenesis in mice and has been linked to chronic kidney disease and directional heart looping in humans. Numerous studies have shown that Shroom3 likely re...

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Detalles Bibliográficos
Autores principales: Das, Debamitra, Zalewski, Jenna K., Mohan, Swarna, Plageman, Timothy F., VanDemark, Andrew P., Hildebrand, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163662/
https://www.ncbi.nlm.nih.gov/pubmed/25171888
http://dx.doi.org/10.1242/bio.20147450