CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation

We have recently generated knockout mice for the Cbx7 gene, coding for a polycomb group protein that is downregulated in human malignant neoplasias. These mice develop liver and lung adenomas and carcinomas, which confirms a tumour suppressor role for CBX7. The CBX7 ability to downregulate CCNE1 exp...

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Detalles Bibliográficos
Autores principales: Forzati, Floriana, Federico, Antonella, Pallante, Pierlorenzo, Colamaio, Marianna, Esposito, Francesco, Sepe, Romina, Gargiulo, Sara, Luciano, Antonio, Arra, Claudio, Palma, Giuseppe, Bon, Giulia, Bucher, Stefania, Falcioni, Rita, Brunetti, Arturo, Battista, Sabrina, Fedele, Monica, Fusco, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163664/
https://www.ncbi.nlm.nih.gov/pubmed/25190058
http://dx.doi.org/10.1242/bio.20147872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163664/
https://www.ncbi.nlm.nih.gov/pubmed/25190058
http://dx.doi.org/10.1242/bio.20147872

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