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Dynamic changes in DNA modification states during late gestation male germ line development in the rat

BACKGROUND: Epigenetic reprogramming of fetal germ cells involves the genome-wide erasure and subsequent re-establishment of DNA methylation. Mouse studies indicate that DNA demethylation may be initiated at embryonic day (e) 8 and completed between e11.5 and e12.5. In the male germline, DNA remethy...

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Detalles Bibliográficos
Autores principales: Rose, Catherine M, van den Driesche, Sander, Sharpe, Richard M, Meehan, Richard R, Drake, Amanda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163680/
https://www.ncbi.nlm.nih.gov/pubmed/25225576
http://dx.doi.org/10.1186/1756-8935-7-19