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Human selenium binding protein-1 (hSP56) is a negative regulator of HIF-1α and suppresses the malignant characteristics of prostate cancer cells

In the present study, we demonstrate that ectopic expression of 56-kDa human selenium binding protein-1 (hSP56) in PC-3 cells that do not normally express hSP56 results in a marked inhibition of cell growth in vitro and in vivo. Down-regulation of hSP56 in LNCaP cells that normally express hSP56 res...

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Detalles Bibliográficos
Autores principales: Jeong, Jee-Yeong, Zhou, Jin-Rong, Gao, Chong, Feldman, Laurie, Sytkowski, Arthur J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163856/
https://www.ncbi.nlm.nih.gov/pubmed/24874852
http://dx.doi.org/10.5483/BMBRep.2014.47.7.104