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Increased 26S proteasome non-ATPase regulatory subunit 1 in the aqueous humor of patients with age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the world. Evidence indicates that the suppression of the ubiquitin-proteasome system (UPS) contributes to the accumulation of toxic proteins and inflammation in retinal pigment epithelium (RPE), the functional abnormalities...

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Detalles Bibliográficos
Autores principales: Lee, Hyungwoo, Choi, Ae Jin, Kang, Gum-Yong, Park, Hyung Soon, Kim, Hyung Chan, Lim, Hyunjung Jade, Chung, Hyewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163863/
https://www.ncbi.nlm.nih.gov/pubmed/24286321
http://dx.doi.org/10.5483/BMBRep.2014.47.5.193