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Inhibitory effects of oroxylin A on endothelial protein C receptor shedding in vitro and in vivo

Endothelial cell protein C receptor (EPCR) plays important roles in blood coagulation and inflammation. EPCR activity is markedly changed by ectodomain cleavage and release as the soluble EPCR. EPCR can be shed from the cell surface, which is mediated by tumor necrosis factor-α converting enzyme (TA...

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Detalles Bibliográficos
Autores principales: Ku, Sae-Kwang, Han, Min-Su, Lee, Min Young, Lee, You-Mie, Bae, Jong-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163868/
https://www.ncbi.nlm.nih.gov/pubmed/24286327
http://dx.doi.org/10.5483/BMBRep.2014.47.6.198