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Structural insights into the transcription-independent apoptotic pathway of p53

Reactivating the p53 pathway in tumors is an important strategy for anticancer therapy. In response to diverse cellular stresses, the tumor suppressor p53 mediates apoptosis in a transcriptionindependent and transcription-dependent manner. Although extensive studies have focused on the transcription...

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Detalles Bibliográficos
Autor principal: Chi, Seung-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163879/
https://www.ncbi.nlm.nih.gov/pubmed/24499665
http://dx.doi.org/10.5483/BMBRep.2014.47.3.261