siRNA-mediated gene silencing of MexB from the MexA-MexB-OprM efflux pump in Pseudomonas aeruginosa

To gain insights into the effect of MexB gene under the short interfering RNA (siRNA), we synthesized 21 bp siRNA duplexes against the MexB gene. RT-PCR was performed to determine whether the siRNA inhibited the expression of MexB mRNA. Changes in antibiotic susceptibility in response to siRNA were...

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Detalles Bibliográficos
Autores principales: Gong, Feng-Yun, Zhang, Ding-Yu, Zhang, Jiang-Guo, Wang, Li-Li, Zhan, Wei-Li, Qi, Jun-Ying, Song, Jian-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163889/
https://www.ncbi.nlm.nih.gov/pubmed/24219865
http://dx.doi.org/10.5483/BMBRep.2014.47.4.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163889/
https://www.ncbi.nlm.nih.gov/pubmed/24219865
http://dx.doi.org/10.5483/BMBRep.2014.47.4.040

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