Cargando…

Spatio-temporal Model for Silencing of the Mitotic Spindle Assembly Checkpoint

The spindle assembly checkpoint arrests mitotic progression until each kinetochore secures a stable attachment to the spindle. Despite fluctuating noise, this checkpoint remains robust and remarkably sensitive to even a single unattached kinetochore among many attached kinetochores; moreover, the ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jing, Liu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163959/
https://www.ncbi.nlm.nih.gov/pubmed/25216458
http://dx.doi.org/10.1038/ncomms5795