Induction of IL-17A Precedes Development of Airway Hyperresponsiveness during Diet-Induced Obesity and Correlates with Complement Factor D

Obesity is a risk factor for the development of asthma. Obese mice exhibit innate airway hyperresponsiveness (AHR), a characteristic feature of asthma, and IL-17A is required for development of AHR in obese mice. The purpose of this study was to examine the temporal association between the onset of...

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Detalles Bibliográficos
Autores principales: Mathews, Joel A., Wurmbrand, Allison P., Ribeiro, Luiza, Neto, Felippe Lazar, Shore, Stephanie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164008/
https://www.ncbi.nlm.nih.gov/pubmed/25309539
http://dx.doi.org/10.3389/fimmu.2014.00440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164008/
https://www.ncbi.nlm.nih.gov/pubmed/25309539
http://dx.doi.org/10.3389/fimmu.2014.00440

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