A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required

The advent of next generation sequencing (NGS) technologies enabled the investigation of the rare variant-common disease hypothesis in unrelated individuals, even on the genome-wide level. Analysis of this hypothesis requires tailored statistical methods as single marker tests fail on rare variants....

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Detalles Bibliográficos
Autores principales: Dering, Carmen, König, Inke R., Ramsey, Laura B., Relling, Mary V., Yang, Wenjian, Ziegler, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164031/
https://www.ncbi.nlm.nih.gov/pubmed/25309579
http://dx.doi.org/10.3389/fgene.2014.00323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164031/
https://www.ncbi.nlm.nih.gov/pubmed/25309579
http://dx.doi.org/10.3389/fgene.2014.00323

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