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Increased Levels of Chitotriosidase and YKL-40 in Cerebrospinal Fluid from Patients with Alzheimer's Disease

BACKGROUND: The cerebrospinal fluid (CSF) biomarkers total tau, abnormally phosphorylated tau and amyloid β 1-42 are strongly associated with Alzheimer's disease (AD). Apart from the pathologic hallmarks that these biomarkers represent, other processes such as inflammation and microglial activa...

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Detalles Bibliográficos
Autores principales: Rosén, Christoffer, Andersson, Carl-Henrik, Andreasson, Ulf, Molinuevo, José L., Bjerke, Maria, Rami, Lorena, Lladó, Albert, Blennow, Kaj, Zetterberg, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164083/
https://www.ncbi.nlm.nih.gov/pubmed/25254036
http://dx.doi.org/10.1159/000362164