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Role of Protein–Protein Interactions in Cytochrome P450-Mediated Drug Metabolism and Toxicity
[Image: see text] Through their unique oxidative chemistry, cytochrome P450 monooxygenases (CYPs) catalyze the elimination of most drugs and toxins from the human body. Protein–protein interactions play a critical role in this process. Historically, the study of CYP–protein interactions has focused...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164225/ https://www.ncbi.nlm.nih.gov/pubmed/25133307 http://dx.doi.org/10.1021/tx500203s |