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Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer

BACKGROUND: Loss of the endosulfatase HSulf-1 is common in ovarian cancer, upregulates heparin binding growth factor signaling and potentiates tumorigenesis and angiogenesis. However, metabolic differences between isogenic cells with and without HSulf-1 have not been characterized upon HSulf-1 suppr...

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Detalles Bibliográficos
Autores principales: Roy, Debarshi, Mondal, Susmita, Wang, Chen, He, Xiaoping, Khurana, Ashwani, Giri, Shailendra, Hoffmann, Robert, Jung, Deok-Beom, Kim, Sung H, Chini, Eduardo N, Periera, Juliana Camacho, Folmes, Clifford D, Mariani, Andrea, Dowdy, Sean C, Bakkum-Gamez, Jamie N, Riska, Shaun M, Oberg, Ann L, Karoly, Edward D, Bell, Lauren N, Chien, Jeremy, Shridhar, Viji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164348/
https://www.ncbi.nlm.nih.gov/pubmed/25225614
http://dx.doi.org/10.1186/2049-3002-2-13