MET and PI3K/mTOR as a Potential Combinatorial Therapeutic Target in Malignant Pleural Mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive disease with a poor prognosis. Studies have shown that both MET and its key downstream intracellular signaling partners, PI3K and mTOR, are overexpressed in MPM. Here we determined the combinatorial therapeutic efficacy of a new generation small...

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Detalles Bibliográficos
Autores principales: Kanteti, Rajani, Dhanasingh, Immanuel, Kawada, Ichiro, Lennon, Frances E., Arif, Qudsia, Bueno, Raphael, Hasina, Rifat, Husain, Aliya N., Vigneswaran, Wickii, Seiwert, Tanguy, Kindler, Hedy L., Salgia, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164360/
https://www.ncbi.nlm.nih.gov/pubmed/25221930
http://dx.doi.org/10.1371/journal.pone.0105919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164360/
https://www.ncbi.nlm.nih.gov/pubmed/25221930
http://dx.doi.org/10.1371/journal.pone.0105919

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