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Recombination Drives Evolution of the Clostridium difficile 16S-23S rRNA Intergenic Spacer Region
PCR-ribotyping, a typing method based on size variation in 16S-23S rRNA intergenic spacer region (ISR), has been used widely for molecular epidemiological investigations of C. difficile infections. In the present study, we describe the sequence diversity of ISRs from 43 C. difficile strains, represe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164361/ https://www.ncbi.nlm.nih.gov/pubmed/25222120 http://dx.doi.org/10.1371/journal.pone.0106545 |