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Recombination Drives Evolution of the Clostridium difficile 16S-23S rRNA Intergenic Spacer Region

PCR-ribotyping, a typing method based on size variation in 16S-23S rRNA intergenic spacer region (ISR), has been used widely for molecular epidemiological investigations of C. difficile infections. In the present study, we describe the sequence diversity of ISRs from 43 C. difficile strains, represe...

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Detalles Bibliográficos
Autores principales: Janezic, Sandra, Indra, Alexander, Rattei, Thomas, Weinmaier, Thomas, Rupnik, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164361/
https://www.ncbi.nlm.nih.gov/pubmed/25222120
http://dx.doi.org/10.1371/journal.pone.0106545