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Microparticles Mediate Hepatic Ischemia-Reperfusion Injury and Are the Targets of Diannexin (ASP8597)

BACKGROUND & AIMS: Ischemia–reperfusion injury (IRI) can cause hepatic failure after liver surgery or transplantation. IRI causes oxidative stress, which injures sinusoidal endothelial cells (SECs), leading to recruitment and activation of Kupffer cells, platelets and microcirculatory impairment...

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Detalles Bibliográficos
Autores principales: Teoh, Narci C., Ajamieh, Hussam, Wong, Heng Jian, Croft, Kevin, Mori, Trevor, Allison, Anthony C., Farrell, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164362/
https://www.ncbi.nlm.nih.gov/pubmed/25222287
http://dx.doi.org/10.1371/journal.pone.0104376