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Microparticles Mediate Hepatic Ischemia-Reperfusion Injury and Are the Targets of Diannexin (ASP8597)
BACKGROUND & AIMS: Ischemia–reperfusion injury (IRI) can cause hepatic failure after liver surgery or transplantation. IRI causes oxidative stress, which injures sinusoidal endothelial cells (SECs), leading to recruitment and activation of Kupffer cells, platelets and microcirculatory impairment...
Autores principales: | Teoh, Narci C., Ajamieh, Hussam, Wong, Heng Jian, Croft, Kevin, Mori, Trevor, Allison, Anthony C., Farrell, Geoffrey C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164362/ https://www.ncbi.nlm.nih.gov/pubmed/25222287 http://dx.doi.org/10.1371/journal.pone.0104376 |
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