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Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis

The genetic background of rheumatoid arthritis (RA) is only partly understood, and several genes seem to be involved. The matrix metalloproteinases MMP1 (interstitial collagenase) and MMP3 (stromelysin 1) are thought to be important in destructive joint changes seen in RA. In the present study, func...

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Detalles Bibliográficos
Autores principales: Dörr, Sylvia, Lechtenböhmer, Nadine, Rau, Rolf, Herborn, Gertraud, Wagner, Ulf, Müller-Myhsok, Bertram, Hansmann, Ingo, Keyszer, Gernot
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416441/
https://www.ncbi.nlm.nih.gov/pubmed/15142265
http://dx.doi.org/10.1186/ar1164