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Nucleolar tethering mediates pairing between the IgH and Myc loci

Gene loci on different chromosomes can preferentially colocalize in the cell nucleus. However, many of the mechanisms mediating this spatial proximity remain to be elucidated. The IgH locus on Chromosome 12 and the Myc locus on Chromosome 15 are a well-studied model for gene colocalization in murine...

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Detalles Bibliográficos
Autores principales: Strongin, Daniel E, Groudine, Mark, Politz, Joan C Ritland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164489/
https://www.ncbi.nlm.nih.gov/pubmed/25482199
http://dx.doi.org/10.4161/nucl.36233