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mTORC1 Is Essential for Early Steps during Schwann Cell Differentiation of Amniotic Fluid Stem Cells and Regulates Lipogenic Gene Expression

Schwann cell development is hallmarked by the induction of a lipogenic profile. Here we used amniotic fluid stem (AFS) cells and focused on the mechanisms occurring during early steps of differentiation along the Schwann cell lineage. Therefore, we initiated Schwann cell differentiation in AFS cells...

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Detalles Bibliográficos
Autores principales: Preitschopf, Andrea, Li, Kongzhao, Schörghofer, David, Kinslechner, Katharina, Schütz, Birgit, Thi Thanh Pham, Ha, Rosner, Margit, Joo, Gabor Jozsef, Röhrl, Clemens, Weichhart, Thomas, Stangl, Herbert, Lubec, Gert, Hengstschläger, Markus, Mikula, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164523/
https://www.ncbi.nlm.nih.gov/pubmed/25221943
http://dx.doi.org/10.1371/journal.pone.0107004