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Aberrant Promoter Methylation of Caveolin-1 Is Associated with Favorable Response to Taxane-Platinum Combination Chemotherapy in Advanced NSCLC

PURPOSE: Aberrant promoter DNA methylation can serve as a predictive biomarker for improved clinical responses to certain chemotherapeutics. One of the major advantages of methylation biomarkers is the ease of detection and clinical application. In order to identify methylation biomarkers predictive...

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Detalles Bibliográficos
Autores principales: Brodie, Seth A., Lombardo, Courtney, Li, Ge, Kowalski, Jeanne, Gandhi, Khanjan, You, Shaojin, Khuri, Fadlo R., Marcus, Adam, Vertino, Paula M., Brandes, Johann C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164573/
https://www.ncbi.nlm.nih.gov/pubmed/25222296
http://dx.doi.org/10.1371/journal.pone.0107124