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Compound A398, a Novel Podophyllotoxin Analogue: Cytotoxicity and Induction of Apoptosis in Human Leukemia Cells

Despite advances in oncology research, cancer is one of the leading causes of death worldwide. Thus, there is a demand for the development of more selective and effective antitumor agents. This study showed that A398, a novel podophyllotoxin analogue, was cytotoxic to the HT-29, MCF-7, MOLT-4 and HL...

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Detalles Bibliográficos
Autores principales: Silveira, Alethéia L., Faheina-Martins, Glaúcia V., Maia, Raquel C., Araújo, Demetrius A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164611/
https://www.ncbi.nlm.nih.gov/pubmed/25221997
http://dx.doi.org/10.1371/journal.pone.0107404