Cargando…
Compound A398, a Novel Podophyllotoxin Analogue: Cytotoxicity and Induction of Apoptosis in Human Leukemia Cells
Despite advances in oncology research, cancer is one of the leading causes of death worldwide. Thus, there is a demand for the development of more selective and effective antitumor agents. This study showed that A398, a novel podophyllotoxin analogue, was cytotoxic to the HT-29, MCF-7, MOLT-4 and HL...
Autores principales: | Silveira, Alethéia L., Faheina-Martins, Glaúcia V., Maia, Raquel C., Araújo, Demetrius A. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164611/ https://www.ncbi.nlm.nih.gov/pubmed/25221997 http://dx.doi.org/10.1371/journal.pone.0107404 |
Ejemplares similares
-
Synthesis and biological activity, and molecular modelling studies of potent cytotoxic podophyllotoxin-naphthoquinone compounds
por: Nguyen, Ha Thanh, et al.
Publicado: (2022) -
Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity
por: Zi, Cheng-Ting, et al.
Publicado: (2019) -
Synthesis and Anticancer Activities of Novel Guanylhydrazone and Aminoguanidine Tetrahydropyran Derivatives
por: Silva, Fábio Pedrosa Lins, et al.
Publicado: (2016) -
Design and Synthesis of Novel Podophyllotoxins Hybrids and the Effects of Different Functional Groups on Cytotoxicity
por: Yang, Zhongtao, et al.
Publicado: (2021) -
Design and Synthesis of 4-O-Podophyllotoxin Sulfamate Derivatives as Potential Cytotoxic Agents
por: Bader, Ammar, et al.
Publicado: (2021)