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Sirtuins: Sir2-related NAD-dependent protein deacetylases

Silent information regulator 2 (Sir2) proteins, or sirtuins, are protein deacetylases dependent on nicotine adenine dinucleotide (NAD) and are found in organisms ranging from bacteria to humans. In eukaryotes, sirtuins regulate transcriptional repression, recombination, the cell-division cycle, micr...

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Detalles Bibliográficos
Autores principales: North, Brian J, Verdin, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416462/
https://www.ncbi.nlm.nih.gov/pubmed/15128440