Carbamazepine Potentiates the Effectiveness of Morphine in a Rodent Model of Neuropathic Pain

Approximately 60% of morphine is glucuronidated to morphine-3-glucuronide (M3G) which may aggravate preexisting pain conditions. Accumulating evidence indicates that M3G signaling through neuronal Toll-like receptor 4 (TLR4) may be central to this proalgesic signaling event. These events are known t...

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Detalles Bibliográficos
Autores principales: Due, Michael R., Yang, Xiao-Fang, Allette, Yohance M., Randolph, Aaron L., Ripsch, Matthew S., Wilson, Sarah M., Dustrude, Erik T., Khanna, Rajesh, White, Fletcher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164621/
https://www.ncbi.nlm.nih.gov/pubmed/25221944
http://dx.doi.org/10.1371/journal.pone.0107399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164621/
https://www.ncbi.nlm.nih.gov/pubmed/25221944
http://dx.doi.org/10.1371/journal.pone.0107399

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