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Expression of the Inherently Autoreactive Idiotope 9G4 on Autoantibodies to Citrullinated Peptides and on Rheumatoid Factors in Patients with Early and Established Rheumatoid Arthritis

BACKGROUND: The pre-symptomatic stage of Rheumatoid arthritis (RA) is associated with pro-inflammatory cytokines and autoantibodies. High levels and epitope spread by Rheumatoid factors (RhF) and autoantibodies to citrullinated proteins signify progression towards disease expression. In established...

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Detalles Bibliográficos
Autores principales: Cambridge, Geraldine, Moura, Rita A., Santos, Tania, Khawaja, Akif A., Polido-Pereira, Joaquim, Canhão, Helena, Leandro, Maria J., Fonseca, João E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164660/
https://www.ncbi.nlm.nih.gov/pubmed/25222933
http://dx.doi.org/10.1371/journal.pone.0107513