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Expression of the Inherently Autoreactive Idiotope 9G4 on Autoantibodies to Citrullinated Peptides and on Rheumatoid Factors in Patients with Early and Established Rheumatoid Arthritis
BACKGROUND: The pre-symptomatic stage of Rheumatoid arthritis (RA) is associated with pro-inflammatory cytokines and autoantibodies. High levels and epitope spread by Rheumatoid factors (RhF) and autoantibodies to citrullinated proteins signify progression towards disease expression. In established...
Autores principales: | Cambridge, Geraldine, Moura, Rita A., Santos, Tania, Khawaja, Akif A., Polido-Pereira, Joaquim, Canhão, Helena, Leandro, Maria J., Fonseca, João E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164660/ https://www.ncbi.nlm.nih.gov/pubmed/25222933 http://dx.doi.org/10.1371/journal.pone.0107513 |
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