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Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance

BACKGROUND: Resistance to thyroid hormone (RTH) is caused by mutations of the thyroid hormone receptor β (TRβ) gene. To understand the transcriptional program underlying TRβ mutant-induced phenotypic expression of RTH, cDNA microarrays were used to profile the expression of 11,500 genes in a mouse m...

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Detalles Bibliográficos
Autores principales: Miller, Lance D, McPhie, Peter, Suzuki, Hideyo, Kato, Yasuhito, Liu, Edison T, Cheng, Sheue-yann
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416467/
https://www.ncbi.nlm.nih.gov/pubmed/15128445