Notch Signaling May Be Involved in the Abnormal Differentiation of Epidermal Keratinocytes in Psoriasis

Localization of each keratin isoform differs among epidermal layers. Proliferating basal cells synthesize keratin 14 (K14) and suprabasal cells express keratin 10 (K10) in normal skin. Notch signaling is essential for keratinocyte differentiation. Notch1 is expressed in all epidermal layers, Notch2...

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Detalles Bibliográficos
Autores principales: Ota, Tami, Takekoshi, Susumu, Takagi, Tatsuya, Kitatani, Kanae, Toriumi, Kentaro, Kojima, Tomoko, Kato, Masayuki, Ikoma, Norihiro, Mabuchi, Tomotaka, Ozawa, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2014
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164705/
https://www.ncbi.nlm.nih.gov/pubmed/25392571
http://dx.doi.org/10.1267/ahc.14027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164705/
https://www.ncbi.nlm.nih.gov/pubmed/25392571
http://dx.doi.org/10.1267/ahc.14027

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