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Elevated recombinant clyA gene expression in the uropathogenic Escherichia coli strain 536, a clue to explain pathoadaptive mutations in a subset of extraintestinal E. coli strains

BACKGROUND: Analysis of the Escherichia coli collection of reference strains (ECOR) for the presence of the gene locus clyA, which encodes the pore-forming protein ClyA (cytolysin A), revealed that a non-functional clyA locus is common among certain extraintestinal pathogenic E. coli (ExPEC). In fac...

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Detalles Bibliográficos
Autores principales: Enow, Constance Oben Ayuk, Oscarsson, Jan, Zlatkov, Nikola, Westermark, Marie, Duperthuy, Marylise, Wai, Sun Nyunt, Uhlin, Bernt Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164713/
https://www.ncbi.nlm.nih.gov/pubmed/25178918
http://dx.doi.org/10.1186/s12866-014-0216-4