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SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes

BACKGROUND/AIMS: SKI306X, a mixed extract of three herbs, Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK), is chondroprotective in animal models of osteoarthritis (OA). The objectives of this study were to investigate its effect on interleukin (IL)-1β-induced degr...

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Detalles Bibliográficos
Autores principales: Choi, Choong Hyeok, Kim, Tae-Hwan, Sung, Yoon-Kyoung, Choi, Chan-Bum, Na, Young-In, Yoo, Hunseung, Jun, Jae-Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164729/
https://www.ncbi.nlm.nih.gov/pubmed/25228841
http://dx.doi.org/10.3904/kjim.2014.29.5.647